> calcium d glucarate

Calcium D Glucarate by Pure EncapsulationsCal cium-d- Glucarate&trade, a patented form of glucaric acid, is a powerful nutrient with the potential to support healthy detoxification and cellular function. In the liver, toxic compounds are bound to glucuronic acids so that they can be eliminated in a safe form from the body in a cleansing process known as glucuronidation. Beta- glucuronidase is a naturally- occurring enzyme found in various organs and cells, which can cleave apart these neutral compounds. d-Glucarate has been shown to help target beta- glucuronidase enzyme activity, supporting the process by which healthy cells eliminate waste and foreign elements. It also helps to maintain healthy cell structure and function. Other studies suggest the promising role of d-glucarate in supporting healthy lipid metabolism. Less

Product Description: Calcium D-Glucarate 90c is available by Douglas Laboratories. amni® original formula A Dietary Supplement 90 Capsules More Info: Calcium D-Glucarate, provided by Douglas Laboratories, is a natural supplement of D-glucaric acid bound to calcium. Calcium D-Glucarate may be a usefuldietary supplement for those who wish to supplement their diet withD-glucaric acid as a precursor to D-glucaro- 1, 4-lactone. Calcium D-glucarate enhances the body’snatural defenses against environmental toxins and excess steroidhormones. Through the actions of its metabolite D-glucaro-1,4-lact one,calcium-d-gluc arate indirectly favors glucuronidation, an importantsystem that the body relies upon to deactivate and eliminate toxins andsteroid hormones. Glucuronidation is a conjugation process throughwhich potentially carcinogenic environmental toxins, such as polycyclicaromati c hydrocarbons and nitrosamines, and excess steroid hormones areneutralized. During glucuronidation, the enzyme glucuronosyltrans ferase catalyzes the conjugation of free carcinogens and steroidhormones to glucuronic acid. The resulting glucuronide- bound toxins andhormones can then be safely excreted in bile and urine. The body alsodeconjugates glucuronide- bound end products. The release ofglucuronide- bound substances is beneficial in some circumstances, forexample, when the excretion of steroid hormones is undesirable. Yet,the deconjugation process, which works via the enzymebeta- glucuronidase, can result in the re-release of harmful toxins backinto the body. The benefits of calcium D-glucarate arerealized indirectly through the action of its metabolite Dglucaro-1,4-lacto ne, which inhibits the deconjugating enzyme beta- glucuronidasefoun d in both blood and tissue. Inhibition of beta- glucuronidase causesa net increase in glucuronidation, and thereby enhances a primarydetoxifica tion pathway in the body. Animal studies have documented adecrease in B-glucuronidase activity in breast, liver, colon, skin,lung, and prostate tissue following oral administration of calciumDglucarate . Once ingested, Calcium D-glucarate is converted toDglucaric acid in the presence of gastric HCl. The body normallymaintains an equilibrium between D-glucaric acid and its twometabolites, D-glucaro-1,4-lact one and D-glucaro-6,3-lact one. CalciumD- glucarate provides a slow-release source of D-glucaro-1,4-lact one.When taken directly, D-glucaro- 1,4-lactone is metabolized quitequickly and is excreted from the body usually within 1-2 hours of itsadministration . Calcium D-glucarate, however, is metabolized slowly,remaining in the body for 5 or more hours after ingestion. This resultsin maintenance of stable levels of D-glucaro-1,4-lact one for longperiods of time. D-glucaric acid is produced endogenously in smallamounts. It is also present in some fruits and vegetables, includingoranges, apples, grapefruit, broccoli and other cruciferous vegetables. Ingredients: Serving Size: 1 Capsule Servings Per Container: 90 Amount Per Serving Calcium ...63mg (From 500 mg of Calcium D-Glucarate) Contains: Gelatin (capsule), Cellulose, Water, Magnesium Stearate Dosage: As a dietary supplement, adults take 1 to 2 capsules daily or as directed by your healthcare professional. WARNINGS: KEEP OUT OF REACH OF CHILDREN. For optimal storage conditions, store in a cool, dry place. (59º-77ºF/15º-25ºC ) (35-65% relative humidity) Tamper resistant package, do not use if outer seal is missing. These statements have not been evaluated by the Food and DrugAdministratio n. These products are not intended to diagnose, treatcure, or prevent any diseases. Less

Why take Calcium D-Glucarate?It is clinically- studied, natural support for healthy estrogen levels? It has been shown to support immune system function, promote estrogen metabolism and enhance the body's detoxification systems.?Why take Calcium D-Glucarate?It has been used in research studies Calcium D-Glucarate is a patented form of D-glucaric acid combined with calcium - the form used in clinical research studies.It has demonstrated benefits for cellular health? Calcium D-Glucarate has been shown to promote healthy estrogen metabolism and support the body's ability to detoxify naturally?Size = 90 UltraCapServing Size = 3If pregnant, nursing, or taking prescription drugs, consult your healthcare practitioner prior to use.This product contains calcium D-glucarate, the use of which is licensed from Applied Food Sciences, LLC, and protected by U.S. patent 4,845,123.ITI evidence-based natural medicines are the only choice of doctors who rely on the fact base of premier science t Less